In uninfected healthy cells, the MHC molecule presents peptides from its own cell (self peptides), to which T cells do not normally react.experiments carried out in mice showed that graft rejection was an immune reaction mounted by the host organism against foreign tissue.
CO;2-5&id=pmid:12362358&genre=article&aulast=Klabunde&aufirst=T.&title=Chem Bio Chem&volume=3&spage=928&epage=944&date=2002&atitle=Drug design strategies for targeting G-protein-coupled receptors&sid=nature: Nature"-adrenergic G-protein-coupled receptor&rfr_id=info:sid/nature.com: Nature.com&id=doi:10.1038/nature07101&id=pmid:18594507&genre=article&aulast=Warne&aufirst=T.&title=Nature&volume=454&spage=486&epage=491&date=2008&atitle=Structure of a &bgr; adrenoceptor&rfr_id=info:sid/nature.com: Nature.com&id=doi:10.1038/nature09648&id=pmid:21228869&genre=article&aulast=Rasmussen&aufirst=S. designed, characterized and screened the constructs, purified the receptor, and prepared the manuscript.
"I think I'm being poisoned," said my husband one morning – not words that any cook wants to hear.
He hadn't been feeling great for a year or more – nausea, splitting headaches, sneezing, puffy eyes and itchy skin – but put it down to hay fever.
"It must be the sandwiches you eat at work," I said defensively, not wanting my cooking to be blamed.
But when he switched to soup at lunch and felt worse than ever, I realised I had to get over myself and started researching food intolerances.